MPG antibody (C-Term)

Catalog No. ABIN2781976

This Rabbit Polyclonal antibody specifically detects MPG in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Horse, Guinea Pig and Rabbit.

Quick Overview for MPG antibody (C-Term) (ABIN2781976)

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MPG Antibody

Binding Specificity: C-Term

Sequence: LEPSEPAVVA AARVGVGHAG EWARKPLRFY VRGSPWVSVV DRVAEQDTQA

Predicted Reactivity: Cow: 85%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MPG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MPG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 293 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MPG

Target: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Alternative Name: MPG

Background: MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Alias Symbols: AAG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg, ADPG
Protein Interaction Partner: HSD17B14, RPA3, RPA2, RPA1, HECW2, UHRF2, LARP4, OBSCN, DHX33, PRPF38B, GNL2, UHRF1, RACGAP1, RRP7A, GNL3, NOC2L, TFIP11, RPRD2, CLASP2, RRP1B, KDM2A, MORF4L1, FXR2, SART1, KHSRP, SRSF1, RFC4, PPP1R10, EXOSC9, PKM, PRDX1, NCBP1, LHCGR, GSN, FLG, KPRP, TWI
Protein Size: 293

Molecular Weight: 32 kDa

Gene ID: 4350

NCBI Accession: NM_001015052, NP_001015052

UniProt: Q5J9I4

Pathways: DNA Damage Repair