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Galactosylceramidase (GALC) (Middle Region) antibody Primary Antibody

GALC Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782035
$389.00
Plus shipping costs $45.00
100 μL
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  • Target
    Galactosylceramidase (GALC)
    Binding Specificity
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 32
    • 20
    • 19
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
    Host
    • 37
    • 3
    Rabbit
    Clonality
    • 37
    • 3
    Polyclonal
    Conjugate
    • 21
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 25
    • 15
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LMTAQEPWSG HYVVESPVWV SAHTTQFTQP GWYYLKTVGH LEKGGSYVAL
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GALC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GALC
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 685 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Galactosylceramidase (GALC)
    Alternative Name
    GALC (GALC Antibody Abstract)
    Synonyms
    galc, galcl, zgc:92561, si:ch211-199l3.4, GALCERase, 2310068B06Rik, A930008M05Rik, AW212969, AW413532, Gacy, twi, twitcher, galactosylceramidase, galactosylceramidase a, Galactosylceramidase, galactosylceramidase L homeolog, GALC, galca, galc, Caci_7107, Bacsa_1415, Spico_0384, LOC100304802, galc.L, Galc
    Background
    GALC is a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy.This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: -
    Protein Interaction Partner: TRAF3,
    Protein Size: 685
    Molecular Weight
    73 kDa
    Gene ID
    2581
    NCBI Accession
    NM_000153, NP_000144
    UniProt
    P54803
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