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P-Cadherin antibody (N-Term)

CDH3 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782138
  • Target See all P-Cadherin (CDH3) Antibodies
    P-Cadherin (CDH3)
    Binding Specificity
    • 16
    • 14
    • 11
    • 9
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse
    Host
    • 92
    • 15
    • 2
    Rabbit
    Clonality
    • 93
    • 16
    Polyclonal
    Conjugate
    • 46
    • 12
    • 11
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P-Cadherin antibody is un-conjugated
    Application
    • 97
    • 50
    • 43
    • 41
    • 19
    • 18
    • 13
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    AVSENGASVE DPMNISIIVT DQNDHKPKFT QDTFRGSVLE GVLPGTSVMQ
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against CDH3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CDH3
    Top Product
    Discover our top product CDH3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 829 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    P-Cadherin (CDH3)
    Alternative Name
    CDH3 (CDH3 Products)
    Synonyms
    CDH3 antibody, Cadherin-3 antibody, AI385538 antibody, Cadp antibody, Cdhp antibody, P-cadherin antibody, Pcad antibody, CDHP antibody, HJMD antibody, PCAD antibody, E-Cad antibody, E-cadherin antibody, EP-cadherin antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, cdh1 antibody, cdh1-b antibody, cdh3 antibody, cdhc-A antibody, cdhp antibody, hjmd antibody, l-cam antibody, lcam antibody, pcad antibody, uvo antibody, uvomorulin antibody, xb-cad antibody, xcdh1 antibody, CDH15 antibody, K-CAM antibody, cadherin 3 antibody, cadherin 3 L homeolog antibody, Cadherin-3 antibody, CDH3 antibody, Cdh3 antibody, cdh3.L antibody, cdh-3 antibody
    Background
    CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
    Alias Symbols: CDHP, HJMD, PCAD
    Protein Interaction Partner: UBC, CTNND1, CTNNB1, CTNNA1, CDH3, JUP, CDH1,
    Protein Size: 829
    Molecular Weight
    91 kDa
    Gene ID
    1001
    NCBI Accession
    NM_001793, NP_001784
    UniProt
    P22223
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