LTB antibody (Lymphotoxin beta (TNF Superfamily, Member 3)) (N-Term)

Details for Product anti-LTB Antibody No. ABIN2782173, Supplier: Log in to see
Antigen
  • AI662801
  • LTbeta
  • Tnfc
  • Tnfsf3
  • p33
  • TNFC
  • TNFSF3
  • LT-b
  • LT-beta
  • TNF-C
  • lymphotoxin B
  • lymphotoxin beta
  • Ltb
  • LTB
Alternatives
anti-Human LTB antibody for Western Blotting
Epitope
N-Term
14
5
4
4
4
2
2
1
1
1
1
1
1
Reactivity
Guinea Pig, Horse (Equine), Human, Rabbit
53
40
19
8
5
4
2
2
2
2
2
Host
Rabbit
64
11
5
Clonality
Polyclonal
Conjugate
This LTB antibody is un-conjugated
7
6
4
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
53
30
17
13
12
12
7
7
4
3
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LTB
Blocking Peptide Blocking peptide for this product available: ABIN979642
Sequence AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
Predicted Reactivity Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%
Characteristics This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others LTB products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name LTB (LTB Antibody Abstract)
Background Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244
Molecular Weight 25 kDa
Gene ID 4050
NCBI Accession NM_002341, NP_002332
UniProt Q06643
Pathways NF-kappaB Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 244 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) antibody (ABIN2782173) WB Suggested Anti-LTB Antibody Titration: 0.2-1 ug/ml Positive Control: Human Thymus
Did you look for something else?