LTB antibody (N-Term)
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- Target See all LTB Antibodies
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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Binding Specificity
- N-Term
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Reactivity
- Human, Horse, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LTB antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
- Predicted Reactivity
- Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LTB
- Top Product
- Discover our top product LTB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 244 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
- Alternative Name
- LTB (LTB Products)
- Synonyms
- AI662801 antibody, LTbeta antibody, Tnfc antibody, Tnfsf3 antibody, p33 antibody, TNFC antibody, TNFSF3 antibody, LT-b antibody, LT-beta antibody, TNF-C antibody, lymphotoxin B antibody, lymphotoxin beta antibody, Ltb antibody, LTB antibody
- Background
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244 - Molecular Weight
- 25 kDa
- Gene ID
- 4050
- NCBI Accession
- NM_002341, NP_002332
- UniProt
- Q06643
- Pathways
- NF-kappaB Signaling
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