ROBO2 antibody (N-Term)

Catalog No. ABIN2782202

Product Details anti-ROBO2 Antibody

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROBO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PQPTVRWKKD DADLPRGRYD IKDDYTLRIK KTMSTDEGTY MCIAENRVGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against ROBO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ROBO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1378 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ROBO2

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Alternative Name: ROBO2 (ROBO2 Products)

Synonyms: SAX3 antibody, ROBO2 antibody, CG14347 antibody, CG14348 antibody, CG5481 antibody, CG5574 antibody, CT17326 antibody, D-Robo2 antibody, D-robo2 antibody, Dmel\\CG5481 antibody, Robo 2 antibody, Robo-2 antibody, Robo2 antibody, anon-EST:Liang-1.75 antibody, clone 1.75 antibody, dRobo-2 antibody, fus4 antibody, robo-2 antibody, robo2 antibody, unp1881 antibody, 2600013A04Rik antibody, 9430089E08Rik antibody, BB097918 antibody, D230004I22Rik antibody, mKIAA1568 antibody, sax3 antibody, roundabout guidance receptor 2 antibody, roundabout 2 antibody, roundabout, axon guidance receptor, homolog 2 (Drosophila) antibody, roundabout guidance receptor 2 S homeolog antibody, ROBO2 antibody, Robo2 antibody, robo2 antibody, robo2.S antibody

Background: ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: KIAA1568, SAX3
Protein Interaction Partner: MYCBP2, Dlg4, MYC, UBQLN4, CENPU, RDH11, TRIM13, RPS6KA5, NR1H2, NR4A1, HLA-DPB1, BNIP3L, OLFM2, PPP1R1B, SSRP1, SLIT2, SLIT3, ROBO1, CPE,
Protein Size: 1378

Molecular Weight: 151 kDa

Gene ID: 6092

NCBI Accession: NM_002942, NP_002933

UniProt: Q9HCK4

Pathways: Regulation of Cell Size