SECTM1 antibody (Middle Region)

Catalog No. ABIN2782205

There is 1 publication for this product available. The Rabbit Polyclonal anti-SECTM1 antibody is suitable to detect SECTM1 in samples from Human. It has been validated for WB.

Quick Overview for SECTM1 antibody (Middle Region) (ABIN2782205)

Target: SECTM1 (Secreted and Transmembrane 1 (SECTM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SECTM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SECTM1 Antibody

Binding Specificity: Middle Region

Purpose: SECTM1 Antibody - middle region

Sequence: ARDSHAGLYM WHLVGHQRNN RQVTLEVSGA EPQSAPDTGF WPVPAVVTAV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SECTM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SECTM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45408-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SECTM1 antibody (ABIN2782205)

Bade-Döding, Göttmann, Baigger, Farren, Lee, Blasczyk, Huyton: "Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7." in: Biochimica et biophysica acta, Vol. 1840, Issue 3, pp. 1004-13, (2014) (PubMed).

Target Details for SECTM1

Target: SECTM1 (Secreted and Transmembrane 1 (SECTM1))

Alternative Name: SECTM1

Background:

Background Information: This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes.

Gene Name: Secreted and transmembrane 1

Alternative Symbols: K12, SECTM

Protein Name: Secreted and transmembrane protein 1

Molecular Weight: 27 kDa

Gene ID: 6398

NCBI Accession: NP_002995

UniProt: Q8WVN6