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IGFBP4 antibody (Middle Region)

IGFBP4 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Sheep, Goat, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782316
  • Target See all IGFBP4 Antibodies
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    Binding Specificity
    • 15
    • 10
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 65
    • 36
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Sheep, Goat, Guinea Pig
    Host
    • 75
    • 13
    • 1
    Rabbit
    Clonality
    • 77
    • 12
    Polyclonal
    Conjugate
    • 38
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGFBP4 antibody is un-conjugated
    Application
    • 80
    • 45
    • 33
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    RALERLAASQ SRTHEDLYII PIPNCDRNGN FHPKQCHPAL DGQRGKCWCV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    Characteristics
    This is a rabbit polyclonal antibody against IGFBP4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human IGFBP4
    Top Product
    Discover our top product IGFBP4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 258 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shi, Chiang, Mistretta, Major, Mori-Akiyama: "SOX9 directly regulates IGFBP-4 in the intestinal epithelium." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 305, Issue 1, pp. G74-83, (2013) (PubMed).

  • Target
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    Alternative Name
    IGFBP4 (IGFBP4 Products)
    Synonyms
    IGFBP4 antibody, igfbp4 antibody, BP-4 antibody, HT29-IGFBP antibody, IBP4 antibody, IGFBP-4 antibody, AI875747 antibody, Deb2 antibody, IGF-BP4 antibody, IBP-4 antibody, insulin like growth factor binding protein 4 antibody, insulin-like growth factor-binding protein 4 antibody, insulin-like growth factor binding protein 4 antibody, IGFBP4 antibody, LOC100136305 antibody, LOC100194498 antibody, igfbp4 antibody, Igfbp4 antibody
    Background
    IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BP-4, HT29-IGFBP, IBP4, IGFBP-4
    Protein Interaction Partner: KDM1A, SUV39H1, Hk3, Hk2, TF, PAPPA, IGF2, IGF1, CTSD,
    Protein Size: 258
    Molecular Weight
    28 kDa
    Gene ID
    3487
    NCBI Accession
    NM_001552, NP_001543
    UniProt
    P22692
    Pathways
    WNT Signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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