Glycogen Synthase 2 antibody (Middle Region)

Catalog No. ABIN2782340

The Rabbit Polyclonal anti-Glycogen Synthase 2 antibody is suitable to detect Glycogen Synthase 2 in samples from Human, Rat, Mouse, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Glycogen Synthase 2 antibody (Middle Region) (ABIN2782340)

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glycogen Synthase 2 Antibody

Binding Specificity: Middle Region

Purpose: GYS2 Antibody - middle region

Sequence: TLSRAFPDKF HVELTSPPTT EGFKYPRPSS VPPSPSGSQA SSPQSSDVED

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GYS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GYS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45727-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glycogen Synthase 2

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Alternative Name: GYS2

Background:

Background Information: GYS2 transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Defects in GYS2 are the cause of glycogen storage disease type 0 (GSD0).

Gene Name: Glycogen synthase 2 (liver)

Alternative Symbols: -

Protein Name: Glycogen [starch] synthase, liver

Molecular Weight: 81 kDa

Gene ID: 2998

NCBI Accession: NP_068776

UniProt: P54840

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process