DYRK1A antibody (N-Term)

Catalog No. ABIN2782362

The Rabbit Polyclonal anti-DYRK1A antibody (ABIN2782362) specifically detects DYRK1A in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse and Dog samples.

Quick Overview for DYRK1A antibody (N-Term) (ABIN2782362)

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYRK1A Antibody

Binding Specificity: N-Term

Sequence: SFHAAGLQMA AQMPHSHQYS DRRQPNISDQ QVSALSYSDQ IQQPLTNQVM

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Dyrk1a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 763 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYRK1A

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Alternative Name: Dyrk1a

Background: Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Dyrk1a phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
Alias Symbols: 2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, ENSMUSG00000074897, Gm10783, MGC150253, MGC150254, Mnbh, Mp86, mmb
Protein Interaction Partner: Rad54l2, Ywhae,
Protein Size: 763

Molecular Weight: 85 kDa

Gene ID: 13548

NCBI Accession: NM_007890, NP_031916

UniProt: Q63470

Pathways: Mitotic G1-G1/S Phases