C21orf33 antibody (N-Term)

Catalog No. ABIN2782372

Product Details anti-C21orf33 Antibody

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C21orf33 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SRGGAEVQIF APDVPQMHVI DHTKGQPSEG ESRNVLTESA RIARGKITDL

Predicted Reactivity: Cow: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against C21orf33. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf33

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 237 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C21orf33

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Alternative Name: C21orf33 (C21orf33 Products)

Synonyms: C21orf33 antibody, es1 antibody, knph antibody, knpi antibody, ES1 antibody, GT335 antibody, HES1 antibody, KNPH antibody, KNPI antibody, chromosome 21 open reading frame, human C21orf33 antibody, chromosome 1 open reading frame, human C21orf33 antibody, chromosome 3 open reading frame, human C21orf33 antibody, chromosome 21 open reading frame 33 antibody, chromosome 21 open reading frame 33 L homeolog antibody, DNA segment, Chr 10, Johns Hopkins University 81 expressed antibody, homolog of zebrafish ES1 antibody, C21H21orf33 antibody, C1H21ORF33 antibody, C3H21orf33 antibody, c21orf33 antibody, C1H21orf33 antibody, c21orf33.L antibody, C21orf33 antibody, D10Jhu81e antibody, RGD1303003 antibody

Background: C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
Alias Symbols: D21S2048E, ES1, GT335, HES1, KNP-I, KNPH, KNPI
Protein Interaction Partner: UBC, SUMO1, NEDD8, APP, FRA10AC1,
Protein Size: 237

Molecular Weight: 21 kDa

Gene ID: 8209

NCBI Accession: NM_198155, NP_937798