CFAP410 antibody (N-Term)

Catalog No. ABIN2782373

The Rabbit Polyclonal anti-CFAP410 antibody is suitable to detect CFAP410 in samples from Human, Cow, Dog, Guinea Pig, Horse, Mouse and Rat. It has been validated for WB.

Quick Overview for CFAP410 antibody (N-Term) (ABIN2782373)

Target: CFAP410 (Cilia and Flagella Associated Protein 410 (CFAP410))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFAP410 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFAP410 Antibody

Binding Specificity: N-Term

Purpose: CFAP410 Antibody - N-terminal region

Sequence: KLTRKMVLTR AKASELHSVR KLNCWGSRLT DISICQEMPS LEVITLSVNS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C21orf2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45819-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFAP410

Target: CFAP410 (Cilia and Flagella Associated Protein 410 (CFAP410))

Alternative Name: CFAP410

Background:

Background Information: Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.

Gene Name: cilia and flagella associated protein 410

Alternative Symbols: RDMS, SMDAX, LRRC76, YF5/A2, C21orf2

Protein Name: protein C21orf2, nuclear encoded mitochondrial protein C21orf2

Molecular Weight: 28kDa

Gene ID: 755

NCBI Accession: NP_004919

UniProt: O43822