CFAP410 antibody (C-Term)

Catalog No. ABIN2782374

The Rabbit Polyclonal anti-CFAP410 antibody (ABIN2782374) specifically detects CFAP410 in WB. The antibody is reactive with Human samples.

Quick Overview for CFAP410 antibody (C-Term) (ABIN2782374)

Target: CFAP410 (Cilia and Flagella Associated Protein 410 (CFAP410))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFAP410 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFAP410 Antibody

Binding Specificity: C-Term

Purpose: CFAP410 Antibody - C-terminal region

Sequence: DPLDSEEEAT SGAQDERGLK PPSRGQFPSL SARDASSSHR GRNVLTAILL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against C21orf2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C21orf2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45820-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFAP410

Target: CFAP410 (Cilia and Flagella Associated Protein 410 (CFAP410))

Alternative Name: CFAP410

Background:

Background Information: Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.

Gene Name: cilia and flagella associated protein 410

Alternative Symbols: RDMS, SMDAX, LRRC76, YF5/A2, C21orf2

Protein Name: protein C21orf2, nuclear encoded mitochondrial protein C21orf2

Molecular Weight: 23kDa

Gene ID: 755

NCBI Accession: NP_004919

UniProt: O43822