SUMO3 antibody (N-Term)

Catalog No. ABIN2782380

The Rabbit Polyclonal anti-SUMO3 antibody is suitable to detect SUMO3 in samples from Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse and Dog. It has been validated for WB.

Quick Overview for SUMO3 antibody (N-Term) (ABIN2782380)

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SUMO3 Antibody

Binding Specificity: N-Term

Purpose: Sumo3 Antibody - N-terminal region

Sequence: PKEGVKTEND HINLKVAGQD GSVVQFKIKR HTPLSKLMKA YCERQGLSMR

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Sumo3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Sumo3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45841-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUMO3

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Alternative Name: Sumo3

Background:

Background Information: Sumo3 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. It does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. It plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.

Gene Name: SMT3 suppressor of mif two 3 homolog 3 (yeast)

Alternative Symbols: SMT, SMT3A, Smt3h, SUMO-3, Smt3h1, D10Ertd345, D10Ertd345e, 2810014B19Rik

Protein Name: Small ubiquitin-related modifier 3

Molecular Weight: 12kDa

Gene ID: 20610

NCBI Accession: NP_064313

UniProt: Q9Z172