DONSON antibody (Middle Region)

Catalog No. ABIN310739

There is 1 publication for this product available. The Rabbit Polyclonal anti-DONSON antibody is suitable to detect DONSON in samples from Human, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog and Rat. It has been validated for WB.

Quick Overview for DONSON antibody (Middle Region) (ABIN310739)

Target: DONSON (Downstream Neighbor of SON (DONSON))

Reactivity: Human, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DONSON antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DONSON Antibody

Binding Specificity: Middle Region

Purpose: DONSON Antibody - middle region

Sequence: DLITALISPT TRGLREAMRN EGIEFSLPLI KESGHKKETA SGTSLGYGEE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DONSON. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DONSON

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099205

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DONSON antibody (ABIN310739)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for DONSON

Target: DONSON (Downstream Neighbor of SON (DONSON))

Alternative Name: DONSON

Background:

Background Information: This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.

Gene Name: Downstream neighbor of SON

Alternative Symbols: B17, MIMIS, MISSLA, C21orf60

Protein Name: Protein downstream neighbor of Son

Molecular Weight: 63kDa

Gene ID: 29980

NCBI Accession: NP_060083

UniProt: Q9NYP3