KRTAP11-1 antibody (N-Term)

Catalog No. ABIN2782415

This Rabbit Polyclonal antibody specifically detects KRTAP11-1 in WB. It exhibits reactivity toward Human.

Quick Overview for KRTAP11-1 antibody (N-Term) (ABIN2782415)

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRTAP11-1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRTAP11-1 Antibody

Binding Specificity: N-Term

Purpose: KRTAP11-1 Antibody - N-terminal region

Sequence: SFNCSTRNCS SRPIGGRCIV PVAQVTTTST TDADCLGGIC LPSSFQTGSW

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against KRTAP11-1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KRTAP11-1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45923-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRTAP11-1

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Alternative Name: KRTAP11-1

Background:

Background Information: KRTAP11-1 belongs to the PMG family. In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Gene Name: Keratin associated protein 11-1

Alternative Symbols: HACL1, HACL-1, KAP11.1

Protein Name: Keratin-associated protein 11-1

Molecular Weight: 17kDa

Gene ID: 337880

NCBI Accession: NP_787054

UniProt: Q8IUC1