KYNU antibody (N-Term)

Catalog No. ABIN2782444

The Rabbit Polyclonal anti-KYNU antibody is suitable to detect KYNU in samples from Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for KYNU antibody (N-Term) (ABIN2782444)

Target: KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KYNU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KYNU Antibody

Binding Specificity: N-Term

Purpose: KYNU Antibody - N-terminal region

Sequence: MEPSSLELPA DTVQRIAAEL KCHPTDERVA LHLDEEDKLR HFRECFYIPK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against KYNU. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KYNU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46036-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KYNU

Target: KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))

Alternative Name: KYNU

Background:

Background Information: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Kynureninase

Alternative Symbols: KYNUU, VCRL2

Protein Name: Kynureninase

Molecular Weight: 52kDa

Gene ID: 8942

NCBI Accession: NP_003928

UniProt: Q16719