MAGEA5 antibody (N-Term)

Catalog No. ABIN2782572

This Rabbit Polyclonal antibody specifically detects MAGEA5 in WB. It exhibits reactivity toward Human.

Quick Overview for MAGEA5 antibody (N-Term) (ABIN2782572)

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGEA5 Antibody

Binding Specificity: N-Term

Purpose: MAGEA5 Antibody - N-terminal region

Sequence: MSLEQKSQHC KPEEGLDTQE EALGLVGVQA ATTEEQEAVS SSSPLVPGTL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEA5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46295-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA5

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Alternative Name: MAGEA5

Background:

Background Information: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Entrez Gene record in accordance with the assumed protein-coding status defined in the literature.

Gene Name: Melanoma antigen family A, 5

Alternative Symbols: CT1.5, MAGE5, MAGEA4, MAGEA5

Protein Name: Melanoma-associated antigen 5

Molecular Weight: 13

Gene ID: 4104

NCBI Accession: NP_066387

UniProt: P43359