MAGEA5 antibody (N-Term)

Catalog No. ABIN2782572

Product Details anti-MAGEA5 Antibody

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSLEQKSQHC KPEEGLDTQE EALGLVGVQA ATTEEQEAVS SSSPLVPGTL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 124 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA5

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Alternative Name: MAGEA5 (MAGEA5 Products)

Synonyms: CT1.5 antibody, MAGE5 antibody, MAGEA4 antibody, Mage-a5 antibody, MAGE family member A5 antibody, melanoma antigen, family A, 5 antibody, MAGEA5 antibody, Magea5 antibody

Background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Entrez Gene record in accordance with the assumed protein-coding status defined in the literature.
Alias Symbols: MAGE5, MAGEA4, MGC129526, CT1.5
Protein Size: 124

Molecular Weight: 13 kDa

Gene ID: 4104

NCBI Accession: NM_021049, NP_066387

UniProt: P43359