MCCC2 antibody (N-Term)

Catalog No. ABIN2782580

This anti-MCCC2 antibody is a Rabbit Polyclonal antibody detecting MCCC2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Goat.

Quick Overview for MCCC2 antibody (N-Term) (ABIN2782580)

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCCC2 Antibody

Binding Specificity: N-Term

Sequence: LPRERIDNLI DPGSPFLELS QFAGYQLYDN EEVPGGGIIT GIGRVSGVEC

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MCCC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MCCC2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2

Background: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
Protein Interaction Partner: HUWE1, SUMO1, NEDD8, MDM2, PARK2, ADRB2, HDAC11, IFIT1, HSPD1, DYNC1H1, UBASH3B, INPPL1, EPS15, CUL3, UBC, EBNA-LP, ICT1, TERF2, TERF1,
Protein Size: 525

Molecular Weight: 57 kDa

Gene ID: 64087