MCCC2 antibody (AA 284-563)

Catalog No. ABIN7268494

This Rabbit Polyclonal antibody specifically detects MCCC2 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MCCC2 antibody (AA 284-563) (ABIN7268494)

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MCCC2 Antibody

Binding Specificity: AA 284-563

Purpose: MCCC2 Rabbit pAb

Sequence: LHLTRKVVRN LNYQKKLDVT IEPSEEPLFP ADELYGIVGA NLKRSFDVRE VIARIVDGSR FTEFKAFYGD TLVTGFARIF GYPVGIVGNN GVLFSESAKK GTHFVQLCCQ RNIPLLFLQN ITGFMVGREY EAEGIAKDGA KMVAAVACAQ VPKITLIIGG SYGAGNYGMC GRAYSPRFLY IWPNARISVM GGEQAANVLA TITKDQRARE GKQFSSADEA ALKEPIIKKF EEEGNPYYSS ARVWDDGIID PADTRLVLGL SFSAALNAPI EKTDFGIFRM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_071415.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2

Background: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.,MCCC2,MCCB,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,MCCC2

Molecular Weight: 57kDa/61kDa

Gene ID: 64087

UniProt: Q9HCC0