MCCC2 antibody (Center)

Catalog No. ABIN2855455

Product Details anti-MCCC2 Antibody

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Xenopus tropicalis

Cross-Reactivity (Details): Rat (88 %), Xenopus laevis (84 %), Zebrafish (84 %), Xenopus tropicalis (85 %)

Characteristics: Rabbit Polyclonal antibody to MCCC2 (methylcrotonoyl-Coenzyme A carboxylase 2 (beta))
MCCC2 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MCCC2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HepG2 , mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2 (MCCC2 Products)

Synonyms: si:dkey-57m14.1 antibody, zgc:85685 antibody, MCCB antibody, 3-METHYLCROTONYL-COA CARBOXYLASE antibody, 3-methylcrotonyl-CoA carboxylase antibody, F28A23.210 antibody, F28A23_210 antibody, 4930552N12Rik antibody, methylcrotonoyl-CoA carboxylase 2 (beta) antibody, methylcrotonoyl-CoA carboxylase 2 antibody, methylcrotonoyl-CoA carboxylase 2 S homeolog antibody, 3-methylcrotonyl-CoA carboxylase antibody, methylcrotonoyl-Coenzyme A carboxylase 2 (beta) antibody, mccc2 antibody, MCCC2 antibody, mccc2.S antibody, Mccc2 antibody, MCCB antibody

Background: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Cellular Localization: Mitochondrion matrix

Molecular Weight: 61 kDa

Gene ID: 64087