GPAA1 antibody (C-Term)

Catalog No. ABIN2782597

The Rabbit Polyclonal anti-GPAA1 antibody has been validated for WB and IHC. It is suitable to detect GPAA1 in samples from Human, Rat, Mouse, Cow, Guinea Pig, Horse, Rabbit and Dog.

Quick Overview for GPAA1 antibody (C-Term) (ABIN2782597)

Target: GPAA1 (GPI Anchor Attachment Protein 1 (GPAA1))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPAA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GPAA1 Antibody

Binding Specificity: C-Term

Sequence: LGSLFLWREL QEAPLSLAEG WQLFLAALAQ GVLEHHTYGA LLFPLLSLGL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GPAA1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GPAA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPAA1

Target: GPAA1 (GPI Anchor Attachment Protein 1 (GPAA1))

Alternative Name: GPAA1

Background: Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. GPAA1 presumably functions in GPI anchoring at the GPI transfer step. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.
Alias Symbols: GAA1, hGAA1
Protein Interaction Partner: UBC, PIGT, PIGU, PRR13, PIGK, EIF3E, PIN1, GRIK5, PIGS,
Protein Size: 621

Molecular Weight: 67 kDa

Gene ID: 8733

NCBI Accession: NM_003801, NP_003792

UniProt: O43292

Pathways: Inositol Metabolic Process, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome