ADAM9 antibody (Middle Region)

Catalog No. ABIN2782602

This Rabbit Polyclonal antibody specifically detects ADAM9 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio).

Quick Overview for ADAM9 antibody (Middle Region) (ABIN2782602)

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM9 Antibody

Binding Specificity: Middle Region

Purpose: ADAM9 Antibody - middle region

Sequence: NKGGNCLLNI PKPDEAYSAP SCGNKLVDAG EECDCGTPKE CELDPCCEGS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ADAM9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADAM9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46373-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAM9

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Alternative Name: ADAM9

Background:

Background Information: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM9 interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.

Gene Name: ADAM metallopeptidase domain 9

Alternative Symbols: MCMP, MDC9, CORD9, Mltng

Protein Name: Disintegrin and metalloproteinase domain-containing protein 9

Molecular Weight: 69kDa

Gene ID: 8754

NCBI Accession: NP_001005845

UniProt: B7ZLN7

Pathways: Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome