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Oncostatin M Receptor antibody (N-Term)

OSMR Reactivity: Human, Dog, Cow WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782612
  • Target See all Oncostatin M Receptor (OSMR) Antibodies
    Oncostatin M Receptor (OSMR)
    Binding Specificity
    • 15
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 51
    • 16
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Dog, Cow
    Host
    • 46
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 49
    • 5
    Polyclonal
    Conjugate
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Oncostatin M Receptor antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    YQSEVLAERL PLTPVSLKVS TNSTRQSLHL QWTVHNLPYH QELKMVFQIQ
    Predicted Reactivity
    Cow: 77%, Dog: 79%, Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against OSMR. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human OSMR
    Top Product
    Discover our top product OSMR Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 979 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Oncostatin M Receptor (OSMR)
    Alternative Name
    OSMR (OSMR Products)
    Synonyms
    OSMRB antibody, PLCA1 antibody, oncostatin M receptor antibody, OSMR antibody, Osmr antibody
    Background
    Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
    Protein Interaction Partner: UBC, CUL5, GAPDH, IL6ST, OSM, JAK2, JAK1, ERBB2,
    Protein Size: 979
    Molecular Weight
    110 kDa
    Gene ID
    9180
    NCBI Accession
    NM_003999, NP_003990
    UniProt
    Q99650
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
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