LARGE antibody (Middle Region)

Catalog No. ABIN2782650

This Rabbit Polyclonal antibody specifically detects LARGE in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Zebrafish (Danio rerio).

Quick Overview for LARGE antibody (Middle Region) (ABIN2782650)

Target: LARGE (Like-Glycosyltransferase (LARGE))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARGE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LARGE Antibody

Binding Specificity: Middle Region

Sequence: AHIMELDVQE YEFIVLPNAY MIHMPHAPSF DITKFRSNKQ YRICLKTLKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LARGE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LARGE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 756 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LARGE

Target: LARGE (Like-Glycosyltransferase (LARGE))

Alternative Name: LARGE

Background: This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of
Alias Symbols: KIAA0609, MDC1D, MDDGA6, MDDGB6
Protein Interaction Partner: DAG1,
Protein Size: 756

Molecular Weight: 88 kDa

Gene ID: 9215

NCBI Accession: NM_004737, NP_004728

UniProt: O95461