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LARGE antibody (AA 35-142) (PE)

LARGE Reactivity: Human FACS Host: Mouse Monoclonal LARGE-02 PE
Catalog No. ABIN5541531
  • Target See all LARGE Antibodies
    LARGE (Like-Glycosyltransferase (LARGE))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-142
    Reactivity
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 6
    • 2
    • 1
    Mouse
    Clonality
    • 8
    • 1
    Monoclonal
    Conjugate
    • 9
    This LARGE antibody is conjugated to PE
    Application
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Thisa ntibody recognizes human LARGE1, a glycosyltransferase localizing mainly to the Golgi apparatus. Crossreactivity with LARGE2 was not determined.
    Immunogen
    Recombinant fragment of human LARGE1 (amino acids 35-142)
    Clone
    LARGE-02
    Isotype
    IgG2b
    Top Product
    Discover our top product LARGE Primary Antibody
  • Application Notes
    Flow cytometry.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    LARGE (Like-Glycosyltransferase (LARGE))
    Alternative Name
    large (LARGE Products)
    Synonyms
    gyltl1b antibody, gyltl1b-b antibody, mdc1d antibody, MDC1D antibody, MDDGA6 antibody, MDDGB6 antibody, BPFD36 antibody, Gyltl1a antibody, Mbp-1 antibody, Mbp1 antibody, enr antibody, fg antibody, froggy antibody, mKIAA0609 antibody, myd antibody, NV15834 antibody, DKFZp459G0120 antibody, LARGE xylosyl- and glucuronyltransferase 1 L homeolog antibody, LARGE xylosyl- and glucuronyltransferase 1 antibody, glycosyltransferase-like protein LARGE1 antibody, like-glycosyltransferase antibody, large1.L antibody, LARGE1 antibody, Large1 antibody, large1 antibody, LOC100118066 antibody, LARGE antibody, Large antibody
    Background
    LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
    UniProt
    O95461
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