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BMP10 antibody (N-Term)

BMP10 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782813
  • Target See all BMP10 Antibodies
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Binding Specificity
    • 15
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 60
    • 25
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 53
    • 7
    • 1
    • 1
    Rabbit
    Clonality
    • 56
    • 6
    Polyclonal
    Conjugate
    • 35
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMP10 antibody is un-conjugated
    Application
    • 54
    • 22
    • 19
    • 13
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Bmp10. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Rat
    Top Product
    Discover our top product BMP10 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 421 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Alternative Name
    Bmp10 (BMP10 Products)
    Synonyms
    BMP10 antibody, si:dkey-13n15.5 antibody, Bmp10 antibody, BMP9 antibody, BMP-10 antibody, bone morphogenetic protein 10 antibody, BMP10 antibody, bmp10 antibody, LOC662386 antibody, Bmp10 antibody
    Background
    Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
    Alias Symbols: Bmp10
    Protein Size: 421
    Molecular Weight
    48 kDa
    Gene ID
    500245
    NCBI Accession
    NM_001031824, NP_001026994
    UniProt
    Q4AEG6
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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