DLL3 antibody (C-Term)

Catalog No. ABIN2782904

This Rabbit Polyclonal antibody specifically detects DLL3 in WB. It exhibits reactivity toward Human, Mouse, Cow and Pig.

Quick Overview for DLL3 antibody (C-Term) (ABIN2782904)

Target: DLL3 (delta Like Protein 3 (DLL3))

Reactivity: Human, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLL3 Antibody

Binding Specificity: C-Term

Purpose: DLL3 Antibody - C-terminal region

Sequence: LVCACAPGYM GARCEFPVHP DGASALPAAP PGLRPGDPQR YLLPPALGLL

Predicted Reactivity: Cow: 86%, Human: 100%, Mouse: 79%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against DLL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DLL3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47291-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Alternative Name: DLL3

Background:

Background Information: This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: delta-like 3 (Drosophila)

Alternative Symbols: SCDO1

Protein Name: Delta-like protein 3

Molecular Weight: 64kDa

Gene ID: 10683

NCBI Accession: NP_982353

UniProt: Q9NYJ7

Pathways: Notch Signaling