RHBDL2 antibody (N-Term)

Catalog No. ABIN2782918

Cited in 1 publication. The Rabbit Polyclonal anti-RHBDL2 antibody (ABIN2782918) specifically detects RHBDL2 in WB. The antibody is reactive with Human samples.

Quick Overview for RHBDL2 antibody (N-Term) (ABIN2782918)

Target: RHBDL2 (Rhomboid, Veinlet-Like 2 (RHBDL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHBDL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHBDL2 Antibody

Binding Specificity: N-Term

Purpose: RHBDL2 Antibody - N-terminal region

Sequence: ELEEEEKMRE DGGGKDRAKS KKVHRIVSKW MLPEKSRGTY LERANCFPPP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RHBDL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RHBDL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47356-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-RHBDL2 antibody (ABIN2782918)

Cheng, Wu, Lin, Hsu, Liu, Chang, Chen, Lai, Shi, Wu: "Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing." in: The Journal of investigative dermatology, Vol. 131, Issue 12, pp. 2486-94, (2011) (PubMed).

Target Details for RHBDL2

Target: RHBDL2 (Rhomboid, Veinlet-Like 2 (RHBDL2))

Alternative Name: RHBDL2

Background:

Background Information: RHBDL2 is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. RHBDL2 is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3.

Gene Name: rhomboid, veinlet-like 2 (Drosophila)

Alternative Symbols: RRP2

Protein Name: Rhomboid-related protein 2, N-terminal fragment Ensembl ENSP00000439227

Molecular Weight: 40kDa

Gene ID: 54933

NCBI Accession: NP_060291

UniProt: B3KUN4