CHST11 antibody (N-Term)

Catalog No. ABIN2782967

This Rabbit Polyclonal antibody specifically detects CHST11 in WB. It exhibits reactivity toward Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for CHST11 antibody (N-Term) (ABIN2782967)

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHST11 Antibody

Binding Specificity: N-Term

Purpose: Chst11 Antibody - N-terminal region

Sequence: RMVLATCFGS FILVIFYFQS MLHPVMRRNP FGVDICCRKG SRSPLQELYN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Chst11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Chst11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47443-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST11

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Alternative Name: Chst11

Background:

Background Information: Chst11 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. It can also sulfate Gal residues in desulfated dermatan sulfate. Chst11 preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. It does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Alternative Symbols: C4s, C4ST, C4ST-, C4ST1, C4ST-1, 1110020P09Rik

Protein Name: Carbohydrate sulfotransferase 11

Molecular Weight: 42kDa

Gene ID: 58250

NCBI Accession: NP_067414

UniProt: Q9JME2

Pathways: Glycosaminoglycan Metabolic Process