FBXO42 antibody (Middle Region)

Catalog No. ABIN2783173

This Rabbit Polyclonal antibody specifically detects FBXO42 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog and Horse.

Quick Overview for FBXO42 antibody (Middle Region) (ABIN2783173)

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO42 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO42 Antibody

Binding Specificity: Middle Region

Purpose: FBXO42 Antibody - middle region

Sequence: RSMDEAPCVN GRWGTLRPRA QRQTPSGSRE GSLSPARGDG SPILNGGSLS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO42. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO42

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47968-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO42

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Alternative Name: FBXO42

Background:

Background Information: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Gene Name: F-box protein 42

Alternative Symbols: JFK, Fbx42

Protein Name: F-box only protein 42

Molecular Weight: 78kDa

Gene ID: 54455

NCBI Accession: NP_061867

UniProt: Q6P3S6