Selenoprotein F antibody (C-Term)

Catalog No. ABIN2783301

The Rabbit Polyclonal anti-Selenoprotein F antibody is suitable to detect Selenoprotein F in samples from Cow, Human, Mouse, Pig, Rat and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Selenoprotein F antibody (C-Term) (ABIN2783301)

Target: Selenoprotein F (SELENOF)

Reactivity: Cow, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selenoprotein F antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Selenoprotein F Antibody

Binding Specificity: C-Term

Purpose: SELENOF Antibody - C-terminal region

Sequence: LFRGLQIKYV RGSDPVLKLL DDNGNIAEEL SILKWNTDSV EEFLSEKLER

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against sep15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat sep15

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48248-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Selenoprotein F

Target: Selenoprotein F (SELENOF)

Alternative Name: SELENOF

Background:

Background Information: The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. Knockout studies in mice also suggest a role for this gene in cataract formation and colon carcinogenesis. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Gene Name: selenoprotein F

Alternative Symbols: 45184

Protein Name: selenoprotein F

Molecular Weight: 17kDa

Gene ID: 113922

NCBI Accession: NP_579831

UniProt: Q923V8