ACAA2 antibody (N-Term)

Catalog No. ABIN2783320

The Rabbit Polyclonal anti-ACAA2 antibody has been validated for WB. It is suitable to detect ACAA2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Horse and Saccharomyces cerevisiae. There is 1 publication available.

Quick Overview for ACAA2 antibody (N-Term) (ABIN2783320)

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACAA2 Antibody

Binding Specificity: N-Term

Sequence: ALLRGVFVVA AKRTPFGAYG GLLKDFTATD LSEFAAKAAL SAGKVSPETV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 91%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ACAA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACAA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 397 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACAA2 antibody (ABIN2783320)

Aboulaich, Vainonen, Strålfors, Vener: "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes." in: The Biochemical journal, Vol. 383, Issue Pt 2, pp. 237-48, (2004) (PubMed).

Target Details for ACAA2

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Alternative Name: ACAA2

Background: ACAA2 catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
Alias Symbols: DSAEC
Protein Interaction Partner: SUMO2, UBC, SGTA, P4HB, H2AFZ, TERT, TMEM65, RTN4, ZFR, TAX1BP3, TOMM40, SF3B4, VDAC2, VDAC1, TP53BP1, TIAL1, VAMP2, PFN1, PRDX1, APP, ACO2, ACAT1, SCP2,
Protein Size: 397

Molecular Weight: 42 kDa

Gene ID: 10449

NCBI Accession: NM_006111, NP_006102

UniProt: P42765

Pathways: Monocarboxylic Acid Catabolic Process