Destrin antibody (N-Term)

Catalog No. ABIN2783326

Product Details anti-Destrin Antibody

Target: Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Destrin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASGVQVADEV CRIFYDMKVR KCSTPEEIKK RKKAVIFCLS ADKKCIIVEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against DSTN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DSTN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 165 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Destrin

Target: Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))

Alternative Name: DSTN (DSTN Products)

Background: DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. It is the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: ACTDP, ADF, bA462D18.2
Protein Interaction Partner: CFL2, ACTG1, ACTB, TAX1BP1, UBC, MDM2, EED, NPM1, ACTA1, SMAD9, STMN2, SEC24A, PDLIM5, DNPH1, LAMTOR5, DPP3, PIEZO1, PUM1, NMI, UBA3, LIMD1, VCP, UBE2B, TTC1, TSTA3, TPM2, STAT6, SP100, ITSN1, SGTA, SRSF2, S100A9, RNH1, PXN, PEX19, PTMS, PTMA, PSMD9, MYH1
Protein Size: 165

Molecular Weight: 18 kDa

Gene ID: 11034

NCBI Accession: NM_006870, NP_006861

UniProt: P60981