MTAP antibody (N-Term)

Catalog No. ABIN2783427

This Rabbit Polyclonal antibody specifically detects MTAP in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse and Zebrafish (Danio rerio).

Quick Overview for MTAP antibody (N-Term) (ABIN2783427)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTAP Antibody

Binding Specificity: N-Term

Purpose: MTAP Antibody - N-terminal region

Sequence: ASGTTTTAVK IGIIGGTGLD DPEILEGRTE KYVDTPFGKP SDALILGKIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MTAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MTAP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48574-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP

Background:

Background Information: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Gene Name: methylthioadenosine phosphorylase

Alternative Symbols: BDMF, MSAP, DMSFH, LGMBF, DMSMFH, c86fus, HEL-249

Protein Name: S-methyl-5'-thioadenosine phosphorylase

Molecular Weight: 38kDa

Gene ID: 4507

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process