MTAP antibody (N-Term)

Catalog No. ABIN2783427

Product Details anti-MTAP Antibody

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASGTTTTAVK IGIIGGTGLD DPEILEGRTE KYVDTPFGKP SDALILGKIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MTAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MTAP

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP (MTAP Products)

Synonyms: BDMF antibody, DMSFH antibody, DMSMFH antibody, LGMBF antibody, MSAP antibody, c86fus antibody, Cc1-6 antibody, 1300019I21Rik antibody, MTAPase antibody, zgc:66012 antibody, mtap antibody, methylthioadenosine phosphorylase antibody, 5'-methylthioadenosine phosphorylase antibody, 6-oxopurine nucleoside phosphorylase antibody, methylthioadenosine phosphorylase L homeolog antibody, MTAP antibody, Mtap antibody, mtaP antibody, MMAH_RS04260 antibody, TAGG_RS05050 antibody, Toce_0364 antibody, VDIS_RS03165 antibody, MFER_RS02485 antibody, Intca_0886 antibody, DESMU_RS05370 antibody, Dester_1490 antibody, ARCVE_RS05445 antibody, Mahau_1873 antibody, MZHIL_RS01440 antibody, mtap antibody, mtap.L antibody

Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Protein Interaction Partner: CENPH, FUS, MTPN, CHRAC1, CUTA, GMPS, UROD, UBE2H, RAB1A, PNP, HPRT1, PDIA3, GOT1, CFL1, ATP6V1A, ANXA6, UBC, RELB, FOLH1, CDC25A, LYRM1, ELAVL1, MYLIP,
Protein Size: 346

Molecular Weight: 38 kDa

Gene ID: 4507

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process