HAT1 antibody (N-Term)

Catalog No. ABIN2783435

The Rabbit Polyclonal anti-HAT1 antibody is suitable to detect HAT1 in samples from Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for HAT1 antibody (N-Term) (ABIN2783435)

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HAT1 Antibody

Binding Specificity: N-Term

Purpose: Hat1 Antibody - N-terminal region

Sequence: FPEDLENDIR TFFPEYTHQL FGDDETAFGY KGLKILLYYI AGSLSTMFRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Hat1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hat1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48609-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: Hat1

Background:

Background Information: Hat1 acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Hat1 has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Hat1 may be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes.

Alternative Symbols: MGC105743

Protein Name: Histone acetyltransferase type B catalytic subunit

Molecular Weight: 46kDa

Gene ID: 296501

NCBI Accession: NP_001009657

UniProt: Q5M939