POLRMT antibody (C-Term)

Catalog No. ABIN2783454

The Rabbit Polyclonal anti-POLRMT antibody is suitable to detect POLRMT in samples from Human, Mouse, Rat, Cow, Guinea Pig, Dog and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for POLRMT antibody (C-Term) (ABIN2783454)

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLRMT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLRMT Antibody

Binding Specificity: C-Term

Sequence: ALGRDSVGAA SVNLEPSDVP QDVYSGVAAQ VEVFRRQDAQ RGMRVAQVLE

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 77%, Rat: 92%, Yeast: 79%

Characteristics: This is a rabbit polyclonal antibody against POLRMT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human POLRMT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLRMT

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Alternative Name: POLRMT

Background: This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Alias Symbols: APOLMT, MTRNAP, MTRPOL, h-mtRPOL
Protein Interaction Partner: UBC, HECW2, TARDBP, CUL3, SIRT7, HDGF, ICT1, KBTBD7, TFB2M, TFB1M,
Protein Size: 1230

Molecular Weight: 135 kDa

Gene ID: 5442

NCBI Accession: NM_005035, NP_005026

UniProt: O00411