ATE1 antibody (Middle Region)

Catalog No. ABIN2783480

This Rabbit Polyclonal antibody specifically detects ATE1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for ATE1 antibody (Middle Region) (ABIN2783480)

Target: ATE1 (Arginyltransferase 1 (ATE1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATE1 Antibody

Binding Specificity: Middle Region

Sequence: TYVWVPIEQC LPSLENSKYC RFNQDPEAVD EDRSTEPDRL QVFHKRAIMP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ATE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 518 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATE1

Target: ATE1 (Arginyltransferase 1 (ATE1))

Alternative Name: ATE1

Background: ATE1 is an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms.This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms.
Alias Symbols: MGC26724
Protein Interaction Partner: EHD1, SUV39H1, UBC, RAE1,
Protein Size: 518

Molecular Weight: 59 kDa

Gene ID: 11101

NCBI Accession: NM_007041, NP_008972

UniProt: O95260

Pathways: SARS-CoV-2 Protein Interactome