PDSS2 antibody (C-Term)

Catalog No. ABIN2783534

This Rabbit Polyclonal antibody specifically detects PDSS2 in WB. It exhibits reactivity toward Human, Dog, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for PDSS2 antibody (C-Term) (ABIN2783534)

Target: PDSS2 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2 (PDSS2))

Reactivity: Human, Dog, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDSS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDSS2 Antibody

Binding Specificity: C-Term

Purpose: PDSS2 Antibody - C-terminal region

Sequence: IKAGKGVTSA IDLCRYHGNK ALEALESFPP SEARSALENI VFAVTRFS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PDSS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PDSS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48856-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDSS2

Target: PDSS2 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2 (PDSS2))

Alternative Name: PDSS2

Background:

Targeted Subunit: 2

Background Information: The isoprenoid chain of ubiquinone (coenzyme Q) varies in length between species and is determined by trans-polyprenyl diphosphate synthase. Humans possess a heterotetrameric decaprenyl diphosphate synthase composed of DPS1 (PDSS1, MIM 607429) and DLP1 (PDSS2) that produces Q10 ubiquinone.The isoprenoid chain of ubiquinone (coenzyme Q) varies in length between species and is determined by trans-polyprenyl diphosphate synthase. Humans possess a heterotetrameric decaprenyl diphosphate synthase composed of DPS1 (PDSS1, MIM 607429) and DLP1 (PDSS2) that produces Q10 ubiquinone (Saiki et al., 2005 [PubMed 16262699]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-24 DC341808.1 2-25 25-1292 BC039906.1 11-1278 1293-2534 AL832290.1 98-1339 2535-2535 BC039906.1 2521-2521 2536-3522 AL832290.1 1340-2326 3523-3568 AL832290.1 2328-2373

Gene Name: Prenyl (decaprenyl) diphosphate synthase, subunit 2

Alternative Symbols: DLP1, COQ1B, hDLP1, COQ10D3, C6orf210, bA59I9.3

Protein Name: Decaprenyl-diphosphate synthase subunit 2

Molecular Weight: 44kDa

Gene ID: 57107

NCBI Accession: NP_065114

UniProt: Q86YH6