Queuine tRNA-Ribosyltransferase Accessory Subunit 2 (QTRT2) (N-Term) antibody

Catalog No. ABIN2783554

This Rabbit Polyclonal antibody specifically detects Queuine tRNA-Ribosyltransferase Accessory Subunit 2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog and Cow.

Quick Overview for Queuine tRNA-Ribosyltransferase Accessory Subunit 2 (QTRT2) (N-Term) antibody (ABIN2783554)

Target: Queuine tRNA-Ribosyltransferase Accessory Subunit 2 (QTRT2)

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: QTRT2 Antibody - N-terminal region

Sequence: YTKTGSAPHL THHTLHNIHG VPAMAQLTLS SLAEHHEVLT EYKEGVGKFI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against QTRTD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human QTRTD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48903-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Queuine tRNA-Ribosyltransferase Accessory Subunit 2 (QTRT2)

Alternative Name: QTRT2

Background:

Targeted Subunit: QTRTD1

Background Information: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: queuine tRNA-ribosyltransferase accessory subunit 2

Alternative Symbols: QTRTD1

Protein Name: queuine tRNA-ribosyltransferase accessory subunit 2

Molecular Weight: 47kDa

Gene ID: 79691

NCBI Accession: NP_078914

UniProt: Q9H974