TTC5 antibody (C-Term)

Catalog No. ABIN2783601

The Rabbit Polyclonal anti-TTC5 antibody (ABIN2783601) specifically detects TTC5 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig and Horse samples.

Quick Overview for TTC5 antibody (C-Term) (ABIN2783601)

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TTC5 Antibody

Binding Specificity: C-Term

Purpose: TTC5 Antibody - C-terminal region

Sequence: GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113735

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Alternative Name: TTC5

Background:

Background Information: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.

Gene Name: Tetratricopeptide repeat domain 5

Alternative Symbols: Strap, NEDCAFD

Protein Name: Tetratricopeptide repeat protein 5

Molecular Weight: 49kDa

Gene ID: 91875

NCBI Accession: NP_612385

UniProt: Q8N0Z6

Pathways: Chromatin Binding