MAP2K7 antibody (Middle Region)

Catalog No. ABIN2783609

This anti-MAP2K7 antibody is a Rabbit Polyclonal antibody detecting MAP2K7 in WB. Suitable for Human, Mouse, Rat, Dog, Sheep, Guinea Pig, Rabbit, Cow, Horse and Zebrafish (Danio rerio).

Quick Overview for MAP2K7 antibody (Middle Region) (ABIN2783609)

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reactivity: Human, Mouse, Rat, Dog, Sheep, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP2K7 Antibody

Binding Specificity: Middle Region

Sequence: ERIDPPDPTK PDYDIRADVW SLGISLVELA TGQFPYKNCK TDFEVLTKVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MAP2K7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAP2K7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 419 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP2K7

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Alternative Name: MAP2K7

Background: MAP2K7 is a stress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
Alias Symbols: Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK4, SAPKK-4
Protein Interaction Partner: MAPK8, MAP3K3, MAP3K2, UBC, FBXO6, MAP3K11, MAPK8IP1, LPXN, VRK2, RPL30, MAPK9, HSP90AA1, ATF4, JUN, WDR6, BCL10, MAP2K4, MAPK1, LRRK2, MAP3K4, MAP3K1, MYC, ELAVL1, ALK, DUSP22, DUSP19, MAPK8IP3, CNKSR1, ZAK, TRIB1, MAPK8IP2, GADD45B, CFLAR, MAP2K7, MAP3K
Protein Size: 419

Molecular Weight: 47 kDa

Gene ID: 5609

NCBI Accession: NM_145185, NP_660186

UniProt: O14733

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling