PRIM2 antibody (Middle Region)

Catalog No. ABIN2783685

The Rabbit Polyclonal anti-PRIM2 antibody (ABIN2783685) specifically detects PRIM2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig and Rabbit samples.

Quick Overview for PRIM2 antibody (Middle Region) (ABIN2783685)

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRIM2 Antibody

Binding Specificity: Middle Region

Purpose: PRIM2 Antibody - middle region

Sequence: QDFLKDSQLQ FEAISDEEKT LREQEIVASS PSLSGLKLGF KSIYKPPFAS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PRIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108905

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRIM2

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Alternative Name: PRIM2

Background:

Background Information: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

Gene Name: Primase, DNA, polypeptide 2 (58 kDa)

Alternative Symbols: p58, PRIM2A

Protein Name: Primase, polypeptide 2A, 58 kDa EMBL CAI40673.1

Molecular Weight: 37kDa

Gene ID: 5558

UniProt: Q5JU42

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interactome