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PCDHA10 antibody (N-Term)

PCDHA10 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783719
  • Target See all PCDHA10 Antibodies
    PCDHA10 (Protocadherin alpha 10 (PCDHA10))
    Binding Specificity
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit
    Host
    • 20
    • 3
    Rabbit
    Clonality
    • 20
    • 3
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHA10 antibody is un-conjugated
    Application
    • 23
    • 16
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    DKDKFPVLVL RKLLDREENP QLKLLLTATD GGKPEFTGSV SLLILVLDAN
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PCDHA10. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA10
    Top Product
    Discover our top product PCDHA10 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 685 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PCDHA10 (Protocadherin alpha 10 (PCDHA10))
    Alternative Name
    PCDHA10 (PCDHA10 Products)
    Synonyms
    CNR8 antibody, CNRN8 antibody, CNRS8 antibody, CRNR8 antibody, PCDH-ALPHA10 antibody, Cnr3 antibody, Cnr8 antibody, Crnr3 antibody, Crnr8 antibody, Pcdha14 antibody, rCNRv10 antibody, protocadherin alpha 10 antibody, PCDHA10 antibody, Pcdha10 antibody
    Background
    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10
    Protein Size: 685
    Molecular Weight
    73 kDa
    Gene ID
    56139
    NCBI Accession
    NM_031860, NP_114066
    UniProt
    A1L493
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