TREM2 antibody (Middle Region)

Catalog No. ABIN2783734

Product Details anti-TREM2 Antibody

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Binding Specificity: Middle Region

Reactivity: Mouse, Human, Rat, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FPGESESFED AHVEHSISRS LLEGEIPFPP TSILLLLACI FLIKILAASA

Predicted Reactivity: Cow: 83%, Horse: 92%, Human: 100%, Mouse: 77%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against TREM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TREM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2 (TREM2 Products)

Synonyms: TREM-A1 antibody, TREM-B1 antibody, TREM2 antibody, trem-2 antibody, trem2a antibody, trem2b antibody, trem2c antibody, TREM-2 antibody, Trem2a antibody, Trem2b antibody, Trem2c antibody, triggering receptor expressed on myeloid cells 2 antibody, trem-like transcript 2 protein antibody, TREM2 antibody, trem2 antibody, LOC100228399 antibody, Trem2 antibody

Background: The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Alias Symbols: TREM-2, Trem2a, Trem2b, Trem2c
Protein Interaction Partner: TYROBP,
Protein Size: 230

Molecular Weight: 25 kDa

Gene ID: 54209

NCBI Accession: NM_018965, NP_061838

UniProt: Q9NZC2