TREM2 antibody (Middle Region)

Catalog No. ABIN2783734

The Rabbit Polyclonal anti-TREM2 antibody is suitable to detect TREM2 in samples from Mouse, Human, Rat, Cow and Horse. It has been validated for WB.

Quick Overview for TREM2 antibody (Middle Region) (ABIN2783734)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Mouse, Human, Rat, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TREM2 Antibody

Binding Specificity: Middle Region

Purpose: TREM2 Antibody - middle region

Sequence: FPGESESFED AHVEHSISRS LLEGEIPFPP TSILLLLACI FLIKILAASA

Predicted Reactivity: Cow: 83%, Horse: 92%, Human: 100%, Mouse: 77%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against TREM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TREM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49413-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background:

Background Information: The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

Gene Name: Triggering receptor expressed on myeloid cells 2

Alternative Symbols: PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c

Protein Name: Triggering receptor expressed on myeloid cells 2

Molecular Weight: 25 kDa

Gene ID: 54209

NCBI Accession: NP_061838

UniProt: Q9NZC2