DLL4 antibody (N-Term)

Catalog No. ABIN2783745

The Rabbit Polyclonal anti-DLL4 antibody (ABIN2783745) specifically detects DLL4 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae samples.

Quick Overview for DLL4 antibody (N-Term) (ABIN2783745)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLL4 Antibody

Binding Specificity: N-Term

Purpose: DLL4 Antibody - N-terminal region

Sequence: QGSLAVGQNW LLDEQTSTLT RLRYSYRVIC SDNYYGDNCS RLCKKRNDHF

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against DLL4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49437-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background:

Background Information: Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. DLL4 plays a role in the Notch signaling pathway. IT activates Notch-1 and Notch-4.This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Delta-like 4 (Drosophila)

Alternative Symbols: AOS6, delta4, hdelta2

Protein Name: Delta-like protein 4

Molecular Weight: 72kDa

Gene ID: 54567

NCBI Accession: NP_061947

UniProt: Q9NR61

Pathways: Notch Signaling