Junctophilin 2 antibody (N-Term)

Catalog No. ABIN2783781

The Rabbit Polyclonal anti-Junctophilin 2 antibody is suitable to detect Junctophilin 2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Junctophilin 2 antibody (N-Term) (ABIN2783781)

Target: Junctophilin 2 (JPH2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Junctophilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Junctophilin 2 Antibody

Binding Specificity: N-Term

Purpose: Jph2 Antibody - N-terminal region

Sequence: QGKRHGLGIE TKGRWLYKGE WTHGFKGRYG IRQSTNSGAK YEGTWNNGLQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Jph2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49509-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Junctophilin 2

Target: Junctophilin 2 (JPH2)

Alternative Name: Jph2

Background:

Background Information: Jph2 contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. It probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development.

Gene Name: Junctophilin 2

Alternative Symbols: JP-, Jp2, JP-2, 1110002E14Rik

Protein Name: Junctophilin-2

Molecular Weight: 75kDa

Gene ID: 59091

NCBI Accession: NP_067541

UniProt: Q9ET78