LIM2 antibody (N-Term)

Catalog No. ABIN2783982

There is 1 publication for this product available. The Rabbit Polyclonal anti-LIM2 antibody is suitable to detect LIM2 in samples from Human. It has been validated for WB.

Quick Overview for LIM2 antibody (N-Term) (ABIN2783982)

Target: LIM2 (Lens Intrinsic Membrane Protein 2, 19kDa (LIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIM2 Antibody

Binding Specificity: N-Term

Purpose: LIM2 Antibody - N-terminal region

Sequence: GSFAHQGLWR YCLGNKCYLQ TDSIGEPPGQ GPGRAWGKSR ADLGAQGHLY

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against LIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49954-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-LIM2 antibody (ABIN2783982)

Wistow, Bernstein, Wyatt, Behal, Touchman, Bouffard, Smith, Peterson: "Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants." in: Molecular vision, Vol. 8, pp. 171-84, (2002) (PubMed).

Target Details for LIM2

Target: LIM2 (Lens Intrinsic Membrane Protein 2, 19kDa (LIM2))

Alternative Name: LIM2

Background:

Background Information: This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: lens intrinsic membrane protein 2

Alternative Symbols: MP17, MP19, CTRCT19

Protein Name: lens fiber membrane intrinsic protein

Molecular Weight: 24kDa

Gene ID: 3982

NCBI Accession: NP_085915

UniProt: P55344

Pathways: Cell-Cell Junction Organization