PIGO antibody (N-Term)

Catalog No. ABIN2784046

This Rabbit Polyclonal antibody specifically detects PIGO in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse and Rabbit.

Quick Overview for PIGO antibody (N-Term) (ABIN2784046)

Target: PIGO (Phosphatidylinositol Glycan Anchor Biosynthesis, Class O (PIGO))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIGO Antibody

Binding Specificity: N-Term

Purpose: PIGO Antibody - N-terminal region

Sequence: LIDALRFDFA QPQHSHVPRE PPVSLPFLGK LSSLQRILEI QPHHARLYRS

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PIGO. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGO

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108015

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGO

Target: PIGO (Phosphatidylinositol Glycan Anchor Biosynthesis, Class O (PIGO))

Alternative Name: PIGO

Background:

Background Information: PIGO is a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGO is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI.This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.

Gene Name: Phosphatidylinositol glycan anchor biosynthesis, class O

Alternative Symbols: HPMRS2

Protein Name: GPI ethanolamine phosphate transferase 3

Molecular Weight: 74kDa

Gene ID: 84720

NCBI Accession: NP_690577

UniProt: B1AML3

Pathways: Inositol Metabolic Process, SARS-CoV-2 Protein Interactome