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SSX4B antibody (Synovial Sarcoma, X Breakpoint 4B) (Middle Region) Primary Antibody

SSX4B Reactivity: Human WB Host: Rabbit Polyclonal
Catalog No. ABIN2784178
$229.00
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100 μL
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  • Target
    Binding Specificity
    Middle Region
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Western Blotting (WB)
    Blocking Peptide
    Blocking peptide for this product available: ABIN984477
    Sequence
    MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SSX4B. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SSX4B
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 188 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Alternative Name
    SSX4B (SSX4B Antibody Abstract)
    Background
    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: SSX4, CT5.4
    Protein Interaction Partner: HIF1A,
    Protein Size: 188
    Molecular Weight
    22 kDa
    Gene ID
    548313
    NCBI Accession
    NM_001034832, NP_001030004
    UniProt
    O60224
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