GTF2A1L antibody (C-Term)

Catalog No. ABIN2784347

The Rabbit Polyclonal anti-GTF2A1L antibody is suitable to detect GTF2A1L in samples from Human, Dog, Horse, Rat and Mouse. It has been validated for WB.

Quick Overview for GTF2A1L antibody (C-Term) (ABIN2784347)

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Reactivity: Human, Dog, Horse, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2A1L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GTF2A1L Antibody

Binding Specificity: C-Term

Purpose: GTF2A1L Antibody - C-terminal region

Sequence: RVTDDDIGEI IQVDGSGDTS SNEEIGSTRD ADENEFLGNI DGGDLKVPEE

Predicted Reactivity: Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against GTF2A1L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2A1L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101417

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2A1L

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Alternative Name: GTF2A1L

Background:

Background Information: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Gene Name: General transcription factor IIA, 1-like

Alternative Symbols: ALF

Protein Name: TFIIA-alpha and beta-like factor

Molecular Weight: 52kDa

Gene ID: 11036

NCBI Accession: NP_006863

UniProt: Q9UNN4